Dr. 伊莱恩·施瓦兹

Dr. 伊莱恩·施瓦兹

Professor, Assistant Dean, External Relations
Co-Program Director of the 教师 for 化学istry 和 Biochemistry
指导教师
Schmid College of Science 和 技术; 化学istry
办公地点: Keck Center for Science 和 Engineering 229
电话: (714) 628-2855
教育:
University of California, Los Angeles, Bachelor of Science
University of California, Los Angeles, Ph.D.

传记

教学

General 化学istry CHEM 140/140L, 150/150L
General 化学istry CHEM 140 和 CHEM 150
Organic 化学istry CHEM 230
化学istry of Health CHEM 103
Introduction to 化学istry & Biochemistry Majors 和 Career Paths CHEM/BCHM 100

就业

  • Associate Dean of External Relations 和 Student Advancement, 澳门威尼斯人app下载大学, 2023-Present
  • Professor, Department of 化学istry, 澳门威尼斯人app下载大学, 2023-Present 
  • Associate Professor, Department of 化学istry, 澳门威尼斯人app下载大学, 2016-2022
  • Assistant Dean of External Relations, 2015-2022
  • Assistant Professor, Department of 化学istry, 澳门威尼斯人app下载大学, 2011-2015
  • Encore Pharmaceuticals, Inc., President 2012-Present
  • Encore Pharmaceuticals, Inc., Vice President 研究 & 发展,2006 - 2011
  • Encore Pharmaceuticals, Inc., Director of 研究 Operations, 2001-2006
  • Assistant 研究 Professor, 医学系, Laboratory of 化学ical Endocrinology, 1998-2008, 1988-1992

研究

发现y, pre-clinical, 和 clinical development of small molecules of medicinal importance. Synthesis 和 evaluation of analogs of gamma-carboxyethylhyroxychroman (CEHC) for the reversible inhibition of the apical 70 pS K+ channel in renal TAL 和 treatment of neuroinflammatory diseases such as Amyotrophic Lateral Sclerosis (ALS). Pharmacologic studies of R-Flurbiprofen 和 other R-NSAIDs (nonsteroidal anti-inflammatory drugs) for treatment of colon 和 prostate cancer 和 Alzheimer's Disease. Chiral control of branched fatty acid oxidation: prevention 和 treatment of obesity 和 related metabolic diseases.

出版物

  • 语法,P.Hamdheydari, L., Benaksas E.J., m, S., Pye, Q.N.怀特,W.J.弗洛伊德,R.A.斯图尔特,C.A.亨斯利,K. (2004) Anti-inflammatory Effects of Tocopherol Metabolites.  BBRC319:1047-1052.
  • 汉斯莱K., Benaksas E.J.博利,R.P .比较.,奶奶,P.Hamdheydari, L., m, S., Pye, Q.斯托达德,M.沃利斯,G.威廉森,K.S.韦斯特,M.怀特,W.J. 弗洛伊德,R.A. (2004)New Perspectives on Vitamin E: Gamma-Tocopherol 和 Carboxyethylhydroxychroman Metabolites in Biology 和 Medicine.  自由基生物学 & 医学,36,1-15.
  • Benaksas E.J.默里,E.D., Jr.怀特,W.J. (1995)利钠激素 II.  Progress in Drug 研究, 45, 245-288.
  • Benaksas E.J.默里,E.D., Jr. 罗杰斯,C.L., Pham, T.加州比戈尔尼亚.E.德温德,S.A.Geibel, R.布鲁巴赫,E.S.怀特,W.J. (1993) Endogenous Natriuretic Factors 1: Sodium Pump Inhibition Does Not Correlate with Natriuretic or Pressor Activities from Uremic Urine.  生命科学.  52, 1045-1054.
  • 克拉姆,唐纳德·J., Benaksas-Schwartz, Elaine J.克诺布勒,卡洛琳. (1992)Host-guest Complexation. 65. Six New Saddle Shaped Hosts Based on Fused Dibenzofuran Units.  J. Am. 化学. Soc.
  • Wechter W.J. 和 Benaksas E.J. (1990)利钠激素.  Progress in Drug 研究 34, 231-257.
  • Benaksas Schwartz, E.J. (1989)Dibenzofuran Cavit和s:  Ribonuclease 和 Serine Protease Mimics 和 a New Method for Synthesizing 4-Aryl Imidazoles.  Ph.D. 论文.(University of California, Los Angeles, 228 pp. 迪斯. Abstr. Int. B. 1989, 50(2), 565.

专利

  • Wechter W.J.古铁雷斯,我., Benaksas Schwartz, E.J.默里,E.D. Jr., USP Appl 20040152777, Therapeutically Active Compounds, Published October 5, 2004.
  • Wechter W.J.默里,E.D. Jr., Benaksas Schwartz, E.J.古铁雷斯,我.D .魁格.D.,美国药典20040152146; Methods for Screening Compounds for Use in the Treatment of Disease, Published October 5, 2004.
  • Wechter W.J., Benaksas Schwartz, E.J.默里,E.D. Jr.古铁雷斯,我., USP Appl 20040151758, 脂肪替代品, Published October 5, 2004.
  • Wechter W.J., Benaksas Schwartz, E.J.,美国药典20040067914; R-NSAID Esters 和 their Use, Published October 3, 2003.
  • Wechter W.J.——小默里. E. D.Kantoci, D.莱文,B., Benaksas Schwartz, E.J., 6,150,402美元; 利钠的化合物2000年11月21日.
  • Wechter W.J.——小默里. E. D.Kantoci, D.莱文,B., Benaksas E.J., usp 6,083,982; 利钠的化合物2000年7月4日.
  • 威廉·J·维特.; Murray, David E.; Kantoci, Darko; Levine, Barry H.; Elaine J . Benaksas., US 94-290430 940815; WO 95-US10411 950815, Natriuretic Cyclic Compounds. 1996年2月22日.

Professional Associations

American 化学ical Society

Awards, Grants 和 研究员hips

  • Principal Investigator National Institutes of Health Grant SBIR Phase II grant, 2 r44 ag023519, Title: Novel CEHC Derivatives for Neuroinflammation, 2004-2008
  • Co-investigator National Institutes of Health Grant SBIR Phase I grant, 1 r43 AG023519, Title: Novel CEHC Derivatives for Neuroinflammation, 2003-2004
  • Co-investigator National Institutes of Health Grant RO1 grant, HL56066, Title: Approaches to Natriuretic 和 Antihypertensive Agents, 1997-2003
  • DuPont 教学 Award, University of California, Los Angeles, 1983